Recombinant muis Galectine-7/Lgals7 eiwit

Lglas7, also known as galectin7, is a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Members of this family have been implicated in a variety of functions, including growth regulation, cell adhesion, migration, neoplastic transformation, and immune responses. It is expressed mainly in stratified squamous epithelium. Lgals7 protein is activated by p53 and repressed by retinoic acid. It is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release. Recombinant mouse Lgals7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques

Lgals7, Galectin-7, Pig1

E.coli

Mouse

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

17.6 kDa (159aa) confirmed by MALDI-TOF

Pig-1, Pig1, Pig 1, Lgals-7, Lgals7, Lgals 7, Galectin-7, Galectin7, Galectin 7, ATGP1759-10 µg, ATGP1759-20 µg, ATGP1759-50 µg, ATGP1759-100 µg, ATGP1759-250 µg, ATGP1759-500 µg, ATGP1759-1 mg, ATGP1759-010, ATGP1759-020, ATGP1759-050, ATGP1759-100, ATGP1759-250, ATGP1759-500, ATGP1759-01M

Magnaldo T., et al. (1995) Dev Biol. 168 (2) :259-71. ; ; Magnaldo T., et al. (1998) Differentiation. 63 (3) :159-68.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 2mM DTT

Cancer

NP_032522

Q9CRB1

Mouse

MGSSHHHHHH SSGLVPRGSH MGSMSATQHK TSLPQGVRVG TVMRIRGMVP DQAGRFHVNL LCGEEQGADA ALHFNPRLDT SEVVFNTKEQ GKWGREERGT GIPFERGQPF EVLLIATEEG FKAVVGDDEY LHFHHRMPPA RVRLVEVGGD VQLHSVKIF