Recombinant muis IL-17RB eiwit

Il17rb, also known as Interleukin-17 receptor B, is a cytokine receptor. This receptor specifically binds to IL17B and IL17E (IL25), but does not bind to IL17 (A) or IL17C. It has been shown to mediate the activation of NF- kB and the production of IL8 induced by IL17E. It was found to be significantly up-regulated during intestinal inflammation, which suggested the immune regulatory activity of this receptor. Recombinant mouse Il17rb, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Interleukin-17 receptor B, Il17rb, Evi27, IL-17ER, IL-17Rh1, Il17br, IL17RH1, IL-17 receptor B, IL-17 receptor homolog 1, Interleukin-17B receptor, IL-17B receptor

Baculovirus

Mouse

HIgG-His-Tag

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

57.1 kDa (511aa)

Interleukin-17B receptor, Interleukin-17 receptor B, Interleukin 17B receptor, Interleukin 17 receptor B, Interleukin17B receptor, Interleukin17 receptor B, IL-17Rh1, IL17RH1, IL 17RH1, Il17rb, IL-17ER, Il17br, IL-17B receptor, IL-17 receptor homolog 1, IL-17 receptor B, IL17B receptor, IL17 receptor homolog 1, IL17 receptor B, IL 17B receptor, IL 17 receptor homolog 1, IL 17 receptor B, IL17 RB, IL 17 RB, Evi27, ATGP3472-10 µg, ATGP3472-20 µg, ATGP3472-50 µg, ATGP3472-100 µg, ATGP3472-250 µg, ATGP3472-500 µg, ATGP3472-1 mg, ATGP3472-010, ATGP3472-020, ATGP3472-050, ATGP3472-100, ATGP3472-250, ATGP3472-500, ATGP3472-01M

Rickel EA. et al., (2008) J. Immunol. 181 (6) :4299-4310.; ; Aggarwal, S. et al., (2002) J. Leukoc. Biol. 71:1-8.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_062529

Q9JIP3

Mouse

Ala

ADPREPTIQC GSETGPSPEW MVQHTLTPGD LRDLQVELVK TSVAAEEFSI LMNISWILRA DASIRLLKAT KICVSGKNNM NSYSCVRCNY TEAFQSQTRP SGGKWTFSYV GFPVELSTLY LISAHNIPNA NMNEDSPSLS VNFTSPGCLN HVMKYKKQCT EAGSLWDPDI TACKKNEKMV EVNFTTNPLG NRYTILIQRD TTLGFSRVLE NKLMRTSVAI PVTEESEGAV VQLTPYLHTC GNDCIRREGT VVLCSETSAP IPPDDNRRML GGVEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H