Recombinant muis LAIR1-eiwit

Lair1, as known as leukocyte-associated immunoglobulin-like receptor 1 isoform a, is an inhibitory receptor of the lg superfamily that is related to inhibitory members of KIR and ILT/CD85 families. This protein is well expressed NK cells, T cells, B cells, monocytes, macrophages, immature neutrophils, dendritic cells and most thymocytes. Also, it functions as an inhibitory receptor not only on NK cells, but on human T cells. Recombinant mouse Lair1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Leukocyte-associated immunoglobulin-like receptor 1 isoform a, Lair1, 5133400O11Rik, BB115266, D7Bwg0421e, Lair-1

Baculovirus

Mouse

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

15kDa (132aa)

LAIR1, Leukocyte-associated immunoglobulin-like receptor 1 isoform a, Lair1, 5133400O11Rik, BB115266, D7Bwg0421e, Lair-1, ATGP3446-10 µg, ATGP3446-20 µg, ATGP3446-50 µg, ATGP3446-100 µg, ATGP3446-250 µg, ATGP3446-500 µg, ATGP3446-1 mg, ATGP3446-10, ATGP3446-20, ATGP3446-50, ATGP3446-100, ATGP3446-250, ATGP3446-500, ATGP3446-1

Tang X., et al. (2012) J. Immunol. 188:548-558.; ; Jiang L., et al. (209) Eur. J. Immunol. 39:1167-1175.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_001106945

Q8BG84

Mouse

Ala

ADPQEGSLPD ITIFPNSSLM ISQGTFVTVV CSYSDKHDLY NMVRLEKDGS TFMEKSTEPY KTEDEFEIGP VNETITGHYS CIYSKGITWS ERSKTLELKV IKENVIQTPA PGPTSDTSWL KTYSIYHHHH HH