Recombinant muis Lipocalin-2/NGAL-eiwit

Lcn2 also known as neutrophil gelatinase-associated lipocalin, belongs to the calycin superfamily and Lipocalin family. LCN2 is an iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. The binding of LCN2 to bacterial siderophores is important in the innate immune response to bacterial infection. Also LCN2 functions as a growth factor. LCN2 is strongly upregulated during inflammation and is upregulated by interleukin 1 (but not TNF alpha) in humans. Recombinant mouse Lcn2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Neutrophil gelatinase-associated lipocalin, 24p3, AW212229, Sip24

E.coli

Mouse

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

23.3 kDa (203aa) confirmed by MALDI-TOF

Lipocalin2, NGAL, Neutrophil gelatinase-associated lipocalin, 24p3, AW212229, Sip24, ATGP3093-10 µg, ATGP3093-20 µg, ATGP3093-50 µg, ATGP3093-100 µg, ATGP3093-250 µg, ATGP3093-500 µg, ATGP3093-1 mg, ATGP3093-10, ATGP3093-20, ATGP3093-50, ATGP3093-100, ATGP3093-250, ATGP3093-500, ATGP3093-1

Yang J., et al. (2002) Mol. Cell 10:1045-1056.; ; Flo T.H., et al. (2004) Nature 432:917-921.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol, 1mM DTT

Immunology

NP_032517

P11672

Mouse

MGSSHHHHHH SSGLVPRGSH MGSQDSTQNL IPAPSLLTVP LQPDFRSDQF RGRWYVVGLA GNAVQKKTEG SFTMYSTIYE LQENNSYNVT SILVRDQDQG CRYWIRTFVP SSRAGQFTLG NMHRYPQVQS YNVQVATTDY NQFAMVFFRK TSENKQYFKI TLYGRTKELS PELKERFTRF AKSLGLKDDN IIFSVPTDQC IDN