Recombinant muis MMP-2-eiwit

MMP-2, also known as Matrix metalloproteinase-2, is one of the f the matrix metalloproteinase (MMP) family.It is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonicdevelopment, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis andmetastasis. It has a role in myocardial cell death pathways and contributes to myocardial oxidative stress byregulating the activity of GSK3beta. This protein cleaves GSK3beta in vitro and involved in the formation of the fibrovascular tissues. Recombinant mouse MMP-2, fused to His-tag at C-terminus, was expressed ininsect cell and purified by using conventional chromatography techniques.

Mmp2, 72 kDa type IV collagenase, 72 kDa gelatinase, Gelatinase A, MMP-2, PEX, Clg4a, GelA, MMP-II, Matrix metalloproteinase-2

Baculovirus

Mouse

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 85% by SDS-PAGE

72.4 kDa (644aa)

MMP2, ATGP3909-10 µg, ATGP3909-20 µg, ATGP3909-50 µg, ATGP3909-100 µg, ATGP3909-250 µg, ATGP3909-500 µg, ATGP3909-1 mg, ATGP3909-10, ATGP3909-20, ATGP3909-50, ATGP3909-100, ATGP3909-250, ATGP3909-500, ATGP3909-1

Shon SM., et al. (2017) Circ J. 81:1528-1536.; ; Wu W., et al. (2018) Cell Cycle. 18:46-59.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Adhesion & Movement

NP_032636.1

P33434

Mouse

Ala

APSPI IKFPGDVAPK TDKELAVQYL NTFYGCPKES CNLFVLKDTL KKMQKFFGLP QTGDLDQNTI ETMRKPRCGN PDVANYNFFP RKPKWDKNQI TYRIIGYTPD LDPETVDDAF ARALKVWSDV TPLRFSRIHD GEADIMINFG RWEHGDGYPF DGKDGLLAHA FAPGTGVGGD SHFDDDELWT LGEGQVVRVK YGNADGEYCK FPFLFNGREY SSCTDTGRSD GFLWCSTTYN FEKDGKYGFC PHEALFTMGG NADGQPCKFP FRFQGTSYNS CTTEGRTDGY RWCGTTEDYD RDKKYGFCPE TAMSTVGGNS EGAPCVFPFT FLGNKYESCT SAGRNDGKVW CATTTNYDDD RKWGFCPDQG YSLFLVAAHE FGHAMGLEHS QDPGALMAPI YTYTKNFRLS HDDIKGIQEL YGPSPDADTD TGTGPTPTLG PVTPEICKQD IVFDGIAQIR GEIFFFKDRF IWRTVTPRDK PTGPLLVATF WPELPEKIDA VYEAPQEEKA VFFAGNEYWV YSASTLERGY PKPLTSLGLP PDVQQVDAAF NWSKNKKTYI FAGDKFWRYN EVKKKMDPGF PKLIADSWNA IPDNLDAVVD LQGGGHSYFF KGAYYLKLEN QSLKSVKFGS IKSDWLGC