Recombinant muis Prolactin eiwit

Prolactin, also known as prl, is a hormone synthesized and secreted by lactotrope cells in the adenohypophysis (anterior pituitary gland) . Prolactin has many effects, the most significant of which is to stimulate the mammary glands to produce milk (lactation) . Increased serum prolactin during pregnancy causes enlargement of the mammary glands of the breasts and increases the production of milk. Recently, prolactin has demonstrated broader roles in breast cancer development, regulation of reproductive function, and immuno-regulation. Recombinant mouse Prolactin, was expressed in E. coli and purified by using conventional chromatography techniques.

Mouse Prolactin stimulates cell proliferation of the Nb2-11 rat lymphoma cells. The ED50 range ≤3 ng/mL.

Prolactin isoform 1, AV290867, Gha1, Prl1a1

E.coli

Mouse

Non-Tagged

SDS-PAGE, Bioactivity

1 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

Measured in a cell proliferation assay using Nb2-11 rat lymphoma cells. The ED50 range ≤3 ng/mL.

22.7 kDa (200aa) confirmed by MALDI-TOF

Prolactin, ATGP3793-10 µg, ATGP3793-20 µg, ATGP3793-50 µg, ATGP3793-100 µg, ATGP3793-250 µg, ATGP3793-500 µg, ATGP3793-1 mg, ATGP3793-10, ATGP3793-20, ATGP3793-50, ATGP3793-100, ATGP3793-250, ATGP3793-500, ATGP3793-1

Suzuki MF., et al. (2012) Biotechnol Appl Biochem. 59 (3) :178-85; ; Goffin V., et al. (1999) Mol Cell Endocrinol. 151 (1-2) :79-87.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4)

Apoptosis

NP_035294

Q9CPQ2

Mouse

MQPLPICSAG DCQTSLRELF DRVVILSHYI HTLYTDMFIE FDKQYVQDRE FMVKVINDCP TSSLATPEDK EQALKVPPEV LLNLILSLVQ SSSDPLFQLI TGVGGIQEAP EYILSRAKEI EEQNKQLLEG VEKIISQAYP EAKGNGIYFV WSQLPSLQGV DEESKILSLR NTIRCLRRDS HKVDNFLKVL RCQIAHQNNC