Recombinant muis S100A6 eiwit

S100 calcium binding protein A6 (S100A6) belongs to the S100 family. S100 family is containing 2 EF-hand calcium-binding motifs. S100 proteins regulate a number of cellular processes such as cell cycle progressions and differentiation. S100A6 plays a role in the reorganization of the actin cytoskeleton and in cell mobility. This is a specific target of S-100B protein in vivo. The binding of S100A6 to S100B is stabilized by S100B-bound calcium and zinc. It associates with both Annexin XI and CacyBP (Calcyclin-binding protein) . It functions to activate several processes along the calcium signal transduction pathway including the regulation of cell growth, proliferation, secretion and exocytosis. Recombinant mouse S100A6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

S100 calcium binding protein A6 (calcyclin), 2A9, 5B10, Cacy, CALCYCLIN, PRA

E.coli

Mouse

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

12.2 kDa (109aa) confirmed by MALDI-TOF

S100A6, S100 calcium binding protein A6 (calcyclin), 2A9, 5B10, Cacy, CALCYCLIN, PRA, ATGP1092-10 µg, ATGP1092-20 µg, ATGP1092-50 µg, ATGP1092-100 µg, ATGP1092-250 µg, ATGP1092-500 µg, ATGP1092-1 mg, ATGP1092-10, ATGP1092-20, ATGP1092-50, ATGP1092-100, ATGP1092-250, ATGP1092-500, ATGP1092-1

Filipek A., et al. (1991) Eur. J. Biochem. 195:795-800; ; Yamashita, N., et al. (1999) J. Comp. Neurol. 404:235-257.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 100 mM NaCl

Signal Transduction

NP_035443

P14069

Mouse

MGSSHHHHHH SSGLVPRGSH MACPLDQAIG LLVAIFHKYS GKEGDKHTLS KKELKELIQK ELTIGSKLQD AEIARLMDDL DRNKDQEVNF QEYVAFLGAL ALIYNEALK