Recombinant muis S100A8 eiwit

S100A8, also known MRP8, is a member of the S100 family, EF-hand superfamily of calcium binding proteins. This protein is localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. It functions both intracellularly and extracellularly, where it binds to RAGE and CD36. Altered expression of this protein is associated with the disease cystic fibrosis. Recombinant mouse S100A8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Protein S100-A8, 60B8Ag, AI323541, B8Ag, Caga, CFAg, CP-10, MRP8, p8

E.coli

Mouse

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

12.4 kDa (109aa) confirmed by MALDI-TOF

S100A8, Protein S100-A8, 60B8Ag, AI323541, B8Ag, Caga, CFAg, CP-10, MRP8, p8, ATGP1085-10 µg, ATGP1085-20 µg, ATGP1085-50 µg, ATGP1085-100 µg, ATGP1085-250 µg, ATGP1085-500 µg, ATGP1085-1 mg, ATGP1085-10, ATGP1085-20, ATGP1085-50, ATGP1085-100, ATGP1085-250, ATGP1085-500, ATGP1085-1

Kerkhoff C., et al. (1999) Biochim. Biophys. 1448 (2) :200-11. ; ; Nacken W., et al. (2003) Biochim. Biophys. 60 (6) :569-80.

Takagi R, et al. S100A9 Increases IL-6 and RANKL Expressions through MAPKs and STAT3 Signaling Pathways in Osteocyte-Like Cells. (Biomed Res Int. 2020) {https://pubmed.ncbi.nlm.nih.gov/32149126/}

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 30% glycerol, 0.1M NaCl,1mM DTT

Cancer

NP_038678.1

P27005

Mouse

MPSELEKALS NLIDVYHNYS NIQGNHHALY KNDFKKMVTT ECPQFVQNIN IENLFRELDI NSDNAINFEE FLAMVIKVGV ASHKDSHKE