Recombinant muis Serpin A9/Centerine eiwit

Serpina9, also known as serpin A9, is a member of the Serpin superfamily of serine protease inhibitors. Serpins are the most broadly distributed superfamily of protease inhibitors that use a conformational change to inhibit target enzymes. They are known to inhibit serine proteases and some are known to inhibit caspases and papain-like cysteine proteases. Serpins are conformational labile and many of the disease-linked mutations of serpins result in misfolding or in pathogenic, inactive polymers. This protein shows inhibition towards trypsin, thrombin, and plasmin and binds DNA and heparin. Recombinant mouse Serpina9, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Serpin A9, Serpin A9, 2310014L03Rik, AW049635, Centerin

Baculovirus

Mouse

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 85% by SDS-PAGE

45.2 kDa (401aa)

Serpin A9, Centerin, Serpin A9 , Serpin A9, 2310014L03Rik, AW049635, Centerin, ATGP3465-10 µg, ATGP3465-20 µg, ATGP3465-50 µg, ATGP3465-100 µg, ATGP3465-250 µg, ATGP3465-500 µg, ATGP3465-1 mg, ATGP3465-10, ATGP3465-20, ATGP3465-50, ATGP3465-100, ATGP3465-250, ATGP3465-500, ATGP3465-1

Law RH., et al. (2006) Genome Biol. 7:216.; ; Paterson MA., et al. (2007) Biochem J. 405:489-494.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_082273

Q9D7D2

Mouse

Asn26

NPYNQESSHL PSMKKNPASQ VSPSNTRFSF LLYQRLAQEN PGQNILFSPV SISTSLAMLS LGARSATKTQ ILRTLGFNFT WVSEPTIHMG FEYLVRSLNK CHQGRELRMG SVLFIRKELQ LQATFLDRVK KLYGAKVFSE DFSNAATAQA QINSYVEKET KGKVVDVIQD LDSQTAMVLV NHIFFKANWT QPFSTANTNK SFPFLLSKGT TVHVPMMHQT ESFAFGVDKE LGCSILQMDY RGDAVAFFVL PGKGKMRQLE KSLSARRLRK WSRSLQKRWI KVFIPKFSIS ASYNLETILP KMGIRDAFNS NADFSGITKT HFLQVSKAAH KAVLDVSEEG TEAAAATTTK LIVRSRDTPS SIIAFKEPFL ILLLDKNTES VLFLGKVENP RKMLEHHHHH H