Recombinant muis TGF-beta 1-eiwit

Members of the Transforming growth factor beta (TGFB) family of cytokines are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. TGFB1 is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. Recombinant mouse TGFB1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Transforming growth factor beta-1, Transforming growth factor beta-1, TGF-beta1, Tgfb, Tgfb-1, TGFbeta1

E.coli

Mouse

His-Tag

SDS-PAGE, Denatured

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

15.2 kDa (135aa)

TGF-b1, ATGP2918-10 µg, ATGP2918-20 µg, ATGP2918-50 µg, ATGP2918-100 µg, ATGP2918-250 µg, ATGP2918-500 µg, ATGP2918-1 mg, ATGP2918-10, ATGP2918-20, ATGP2918-50, ATGP2918-100, ATGP2918-250, ATGP2918-500, ATGP2918-1

Assoian RK, Komoriya A, et al. (1983) . J Biol Chem. 258 (11) :7155-60.; ; Choy L, et al. (1998) . J Biol Chem. 273 (47) :31455-62.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Hormones & Cytokines

NP_035707

P04202

Mouse

ALDTNYC FSSTEKNCCV RQLYIDFRKD LGWKWIHEPK GYHANFCLGP CPYIWSLDTQ YSKVLALYNQ HNPGASASPC CVPQALEPLP IVYYVGRKPK VEQLSNMIVR SCKCS