Recombinant muizen TLR2-eiwit

Tlr2, also known as toll-like receptor 2, is a member of the Toll-like receptor (TLR) family. It is typically thought to recognize bacterial components, it has been described to alter the induction of both innate and adaptive immunity to a number of viruses, including vaccinia virus (VACV) . It may recognize virus preparations in vitro and have a minor role in preventing dissemination of VACV following systemic infection with large doses of virus. it is wholly disposable in both control of virus replication and induction of adaptive immunity following intradermal infection. Recombinant mouse Tlr2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Toll-like receptor 2, Tlr2, Ly105

Baculovirus

Mouse

HIgG-His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 85% by SDS-PAGE

90.7 kDa (805aa)

TLR2, Toll-like receptor 2, Tlr2, Ly105, ATGP3597-10 µg, ATGP3597-20 µg, ATGP3597-50 µg, ATGP3597-100 µg, ATGP3597-250 µg, ATGP3597-500 µg, ATGP3597-1 mg, ATGP3597-10, ATGP3597-20, ATGP3597-50, ATGP3597-100, ATGP3597-250, ATGP3597-500, ATGP3597-1

Davies ML., et al. (2014) J Virol. 88:3557-3567.; ; Yueh MF., et al. (2014) J Biol Chem. 289:4699-4709.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_036035

Q9QUN7

Mouse

Ala

ADLQESLSCD ASGVCDGRSR SFTSIPSGLT AAMKSLDLSF NKITYIGHGD LRACANLQVL MLKSSRINTI EGDAFYSLGS LEHLDLSDNH LSSLSSSWFG PLSSLKYLNL MGNPYQTLGV TSLFPNLTNL QTLRIGNVET FSEIRRIDFA GLTSLNELEI KALSLRNYQS QSLKSIRDIH HLTLHLSESA FLLEIFADIL SSVRYLELRD TNLARFQFSP LPVDEVSSPM KKLAFRGSVL TDESFNELLK LLRYILELSE VEFDDCTLNG LGDFNPSESD VVSELGKVET VTIRRLHIPQ FYLFYDLSTV YSLLEKVKRI TVENSKVFLV PCSFSQHLKS LEFLDLSENL MVEEYLKNSA CKGAWPSLQT LVLSQNHLRS MQKTGEILLT LKNLTSLDIS RNTFHPMPDS CQWPEKMRFL NLSSTGIRVV KTCIPQTLEV LDVSNNNLDS FSLFLPRLQE LYISRNKLKT LPDASLFPVL LVMKIRENAV STFSKDQLGS FPKLETLEAG DNHFVCSCEL LSFTMETPAL AQILVDWPDS YLCDSPPRLH GHRLQDARPS VLECHQLEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGKH HHHHH