Recombinant NF-κB1 p105/p50 Monoklonale antilichamen

Nuclear factor kappa B subunit 1 (NFKB1) Homo sapiens This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth.

NF-κB1 p105/p50

P25799

Human; Mouse; Rat

Recombinant Human NF-κB1 p105/p50 protein

NFKB; Nfkb1; EBP-1; KBF1; NF-Kappa-B; NF-KB1; NFKB-p105; NFKB-p50; p105; p50; NFKB1

4F9

Unconjugated

WB

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/YiRAIfI5

50 kDa,105 kDa

50 kDa,120 kDa

IgG, κ