Recombinant PD-L1 Monoklonale Antilichaam

PD-1 is an immunoinhibitory receptor expressed by activated T cells, B cells, and myeloid cells. Engagement of PD-1 by PD-L1 leads to the inhibition of T cell receptor–mediated lymphocyte proliferation and cytokine secretion. In addition, PD-1 signaling can inhibit at least suboptimal levels of CD28-mediated costimulation. PD-L1 is expressed by antigen-presenting cells, including human peripheral blood monocytes stimulated with interferong, and activated human and murine dendritic cells.

PD-L1

Q9NZQ7

Human

Recombinant human PD-L1 fragment

PDL; B7H; PD-L; PD1L; Programmed cell death 1 ligand; PDCD1L; PDCD1LG; B7-H; B7H1; PDL1; PD-L1; PDCD1L1; PDCD1LG1; CD274; B7-H1; B7 homolog 1; CD274 molecule; PDCD1 ligand 1; Programmed death ligand 1; PD1L1; Programmed cell death 1 ligand 1; PDL1; PD-L1; B7-H; B7H1; CD274 molecule; PDCD1L1; PDCD1LG1; B7 H; B7 H1; CD 274; CD274 antigen; MGC142294; MGC142296; OTTHUMP00000021029; PD L1; PDL 1; RGD1566211

A326

Unconjugated

WB; IHC

Immunology; Cancer

Protein A purified

1 mg/mL

WB 1:500-1:2000; IHC 1:200-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/XG8jtAaj

33 kDa

50 kDa

IgG, κ