Recombinant PDK2 monoklonaal antilichaam

[Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 2 (PDK2) is a kinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. PDK2 Mediates cellular responses to insulin and plays an important role in maintaining normal blood glucose levels and in metabolic adaptation to nutrient availability.

PDK2

Q15119

Human; Rat; Mouse

Recombinant human PDK2 fragment

PDK; PDHK; Pyruvate dehydrogenase kinase isoform; Pyruvate dehydrogenase lipoamide kinase isozyme; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme; isozyme; PDK2; PDHK2; PDKII; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2; isozyme 2; mitochondrial; Pyruvate dehydrogenase kinase; Pyruvate dehydrogenase kinase isoform 2; Pyruvate dehydrogenase lipoamide kinase isozyme 2

A433

Unconjugated

WB

Signal Transduction; Cancer; Metabolism

Protein A purified

1 mg/mL

WB 1:1000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/mtWbPs1g

46 kDa

46 kDa

IgG, κ