Recombinant PI3 Kinase p110 alfa Monoklonale antilichamen

Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns (4,5) P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3) . PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors.

PI3 Kinase p110 alpha

P42336

Human; Rat; Mouse

Recombinant human PI3 Kinase p110 alpha fragment

CWS; PIK3CA; CLOVE; CWS5; MCAP; MCM; MCMTC; PI3K; PI3K-alpha;5 bisphosphate 3 kinase 110 kDa catalytic subunit alpha;5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha;5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (PtdIns-3-kinase subunit p110-alpha;5-bisphosphate 3-kinase catalytic subunit alpha isoform; caPI3K; MGC142161; MGC142163; p110 alpha; p110alpha; Phosphatidylinositol 3 kinase catalytic 110 KD alpha; Phosphatidylinositol 3 kinase catalytic alpha polypeptide; Phosphatidylinositol 4; Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha; Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha isoform; Phosphatidylinositol-4; Phosphoinositide 3 kinase catalytic alpha polypeptide; Phosphoinositide 3-kinase alpha; Phosphoinositide-3-kinase catalytic alpha polypeptide; PI3 kinase p110 subunit alpha; PI3Kalpha; PI3KC A; PI3-kinase subunit alpha; PIK3C A; PK3CA; PtdIns 3 kinase p110; PtdIns-3-kinase subunit alpha; PtdIns-3-kinase subunit p110-alpha; Serine/threonine protein kinase PIK3CA

A333

Unconjugated

WB; IHC; IF

Signal Transduction; Cancer; Immunology

Protein A purified

1 mg/mL

WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:50

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/KJwWghaU

110 kDa

120 kDa

IgG, κ