Recombinant PPM1A Monoklonale Antilichaam

Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.

PPM1A

P35813

Human; Mouse

Recombinant human PPM1A fragment

PPM1A; PP2C-ALPHA; PP2CA; PP2Calpha; Protein Phosphatase 1A; Protein Phosphatase 2C Isoform Alpha; Protein Phosphatase IA; PPPM1A

A336

Unconjugated

WB; IHC

Signal Transduction

Protein A purified

1 mg/mL

WB 1:500-1:1000; IHC 1:50-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/4w0BAP3f

42 kDa

42 kDa

IgG, κ