Recombinant PRAME monoklonaal antilichaam

This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.

PRAME

P78395

Human

Recombinant human PRAME fragment

OIP; PRAME; CT130; MAPE; OIP-4; OIP4;4930534P07Rik; Cancer/testis antigen 130; Melanoma antigen preferentially expressed in tumors; OIP 4; OIP4; OPA interacting protein 4; Opa interacting protein OIP4; OPA-interacting protein 4; Preferentially expressed antigen in melanoma; Preferentially expressed antigen of melanoma; RP23-250F8.3

A513

Unconjugated

WB

Tags & Cell Markers; Epigenetics and Nuclear Signaling; Cancer

Protein A purified

1 mg/mL

WB 1:500-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/NIIdre0Y

58 kDa

58 kDa

IgG, κ