Recombinant rat ACE-2-eiwit

ACE2, also known as angiotensin-converting enzyme 2, is carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. It is able to hydrolyze apelin-13 and dynorphin-13 with high efficiency and may be an important regulator of heart function. Recombinant rat ACE2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

ACE2, angiotensin-converting enzyme2, Ace2, ACE-related carboxypeptidase

Baculovirus

Rat

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

84.7 kDa (731aa)

ACE2, ACE2, ATGP3265-10 µg, ATGP3265-20 µg, ATGP3265-50 µg, ATGP3265-100 µg, ATGP3265-250 µg, ATGP3265-500 µg, ATGP3265-1 mg, ATGP3265-10, ATGP3265-20, ATGP3265-50, ATGP3265-100, ATGP3265-250, ATGP3265-500, ATGP3265-1

Li W., et al. (2004) J. Virol. 78:11429-11433.; ; Crackower M., A. et al. (2002) Nature 417:822-828.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Enzymes & Proteases

NP_001012006.1

Q5EGZ1

Rat