Recombinant rat IL-2-eiwit

IL-2, also known as T cell growth factor (TCGF), is an immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. Il-2/ Il-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant rat IL-2 was expressed in E. coli and purified by using conventional chromatography techniques.

Rat IL-2 stimulates cell proliferation of the CTLL2 mouse cytotoxic T cells. The ED50 range is less or equal to 0.3 ng/mL.

Interleukin-2, IL-2, T-cell growth factor, TCGF

E.coli

Rat

Non-Tagged

SDS-PAGE, Bioactivity

0.25 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

Measured in a cell proliferation assay using CTLL2 mouse cytotoxic T cells. The ED50 for this effect is less or equal to 0.3 ng/mL.

15.6 kDa (136aa) confirmed by MALDI-TOF

IL2, ATGP3889-10 µg, ATGP3889-20 µg, ATGP3889-50 µg, ATGP3889-100 µg, ATGP3889-250 µg, ATGP3889-500 µg, ATGP3889-1 mg, ATGP3889-10, ATGP3889-20, ATGP3889-50, ATGP3889-100, ATGP3889-250, ATGP3889-500, ATGP3889-1, ATGP3889-10 µg, ATGP3889-20 µg, ATGP3889-50 µg, ATGP3889-100 µg, ATGP3889-250 µg, ATGP3889-500 µg, ATGP3889-1 mg, ATGP3889-10, ATGP3889-20, ATGP3889-50, ATGP3889-100, ATGP3889-250, ATGP3889-500, ATGP3889-1

Watson J., et al. (1980) . Immunol Rev. 51:257-78.; ; Taniguchi T., et al. (1983) . Nature. 302 (5906) : 305-10.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Hormones & Cytokines

NP_446288

P17108

Rat

MAPTSSPAKE TQQHLEQLLL DLQVLLRGID NYKNLKLPMM LTFKFYLPKQ ATELKHLQCL ENELGALQRV LDLTQSKSFH LEDAGNFISN IRVTVVKLKG SENKFECQFD DEPATVVEFL RRWIAICQSI ISTMTQ