Recombinant rat IL-33 eiwit

Il33 also known as Interleukin-33. Il33 induces production of large amounts of IL5 and IL13 by group 2 innate lymphoid cells (ILC2s), for initiation of allergic inflammation shortly after exposure to allergens or infection with parasites or viruses. Il33 appears to function as an alarmin (alarm signal) rapidly released from producing cells upon cellular damage or cellular stress. Recombinant rat Il33, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Interleukin-33

E.coli

Rat

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

19.8 kDa (179aa) confirmed by MALDI-TOF

IL33, Interleukin-33, ATGP3167-10 µg, ATGP3167-20 µg, ATGP3167-50 µg, ATGP3167-100 µg, ATGP3167-250 µg, ATGP3167-500 µg, ATGP3167-1 mg, ATGP3167-10, ATGP3167-20, ATGP3167-50, ATGP3167-100, ATGP3167-250, ATGP3167-500, ATGP3167-1

Cayrol C., et al. (2014) Current Opinion in Immunology. 31:31-37. ; ; Pomeshchik Y., et al. (2015) Brain Behavior Immunity. 44:68-81

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Hormones & Cytokines

NP_001014188

Q66H70

Rat

SIQGTSL LTESCALSTY NDQSVSFVLE NGCYVINVED CGKNQEKDKV LLRYYESSFP AQSGDGVDGK KLMVNMSPIK DTDIWLNAND KDYSVELQKG DVSPPDQAFF VLHKKSSDFV SFECKNLPGT YIGVKDNQLA LVEENDESCN NIMFKLSKM