Recombinant rat Neuropiline 1/NRP1-eiwit

Nrp1, also known as neuropilin-1, is a transmembrane glycoprotein that regulates axon guidance and angiogenesis. It acts as a receptor for two different extracellular ligands, class 3 semaphorins and specific isoforms of vascular endothelial growth factor. It is likely to mediate contacts between the dendritic cells and the T lymphocytes via homotypic interactions and is essential for the initiation of the primary immune response. Recombinant rat Nrp1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Neuropilin-1, Nrp1, NRP, Vascular endothelial cell growth factor 165 receptor, CD304

Baculovirus

Rat

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

94.8 kDa (842aa)

Neuropilin1, Neuropilin-1, Nrp1, NRP, ATGP3362-10 µg, ATGP3362-20 µg, ATGP3362-50 µg, ATGP3362-100 µg, ATGP3362-250 µg, ATGP3362-500 µg, ATGP3362-1 mg, ATGP3362-10, ATGP3362-20, ATGP3362-50, ATGP3362-100, ATGP3362-250, ATGP3362-500, ATGP3362-1

Bielenberg DR., et al. (2006) Exp Cell Res. 312:584-593.; ; Soker S., et al. (1998) Cell. 92:735-745.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

NP_659566.1

Q9QWJ9

Rat

Phe22