Recombinant rat Peroxiredoxin 2/PRDX2-eiwit

Prdx2 also known as peroxiredoxin-2 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Prdx2 may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8 (+) T-cells. If Prdx2 protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer. Recombinant rat Prdx2, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Peroxiredoxin-2, Thiol-specific antioxidant protein, TSA, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, Thioredoxin-dependent peroxiredoxin 2, Tdpx1

E.coli

Rat

His-Tag

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

> 90% by SDS-PAGE

24.3 kDa (222aa) confirmed by MALDI-TOF

Peroxiredoxin2, Prdx2, Peroxiredoxin-2, ATGP3147-10 µg, ATGP3147-20 µg, ATGP3147-50 µg, ATGP3147-100 µg, ATGP3147-250 µg, ATGP3147-500 µg, ATGP3147-1 mg, ATGP3147-10, ATGP3147-20, ATGP3147-50, ATGP3147-100, ATGP3147-250, ATGP3147-500, ATGP3147-1

Kim H S., et al (2009) . Oncol Rep. 21 (6) :1391-6.; ; Kim J H., et al (2008) . Clin Cancer Res. 14 (8) :2326-33.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol1mM DTT

Redox Proteins

NP_058865

P35704

Rat

MGSSHHHHHH SSGLVPRGSH MGSHMASGNA HIGKPAPDFT GTAVVDGAFK EIKLSDYRGK YVVLFFYPLD FTFVCPTEII AFSDHAEDFR KLGCEVLGVS VDSQFTHLAW INTPRKEGGL GPLNIPLLAD VTKSLSQNYG VLKNDEGIAY RGLFIIDAKG VLRQITVNDL PVGRSVDEAL RLVQAFQYTD EHGEVCPAGW KPGSDTIKPN VDDSKEYFSK HN