Recombinant rat Profiline 1/PFN1-eiwit

Pfn1 also known as Profilin-1 is a ubiquitous actin monomer-binding protein belonging to the profilin family. This protein significantly enhances skin wound healing in-vitro and in-vivo that may be mediated by purinergic receptors. It is also active in endothelial cell migration and vessel sprouting. It is thought to regulate actin polymerization in response to extracellular signals. Recombinant rat Pfn1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Profilin-1, Profilin, Pfn1

E.coli

Rat

His-Tag

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

> 95% by SDS-PAGE

17.5 kDa (164aa) confirmed by MALDI-TOF

Profilin-I, ProfilinI, Profilin-1, Profilin1, Profilin I, Profilin 1, PFN-1, PFN1, PFN 1, Pfn, Actin binding protein, ATGP3173-10 µg, ATGP3173-20 µg, ATGP3173-50 µg, ATGP3173-100 µg, ATGP3173-250 µg, ATGP3173-500 µg, ATGP3173-1 mg, ATGP3173-010, ATGP3173-020, ATGP3173-050, ATGP3173-100, ATGP3173-250, ATGP3173-500, ATGP3173-01M

Tamura M., et al (1996) Biochem. Biophys. Res. Commun. 222 (3) :683-7.; ; Cheng YJ., et al (2015) World Gastroenterol. 21 (8) :2323-35.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol1mM DTT

Cytoskeleton

NP_071956

P62963

Rat

MGSSHHHHHH SSGLVPRGSH MGSHMAGWNA YIDSLMADGT CQDAAIVGYK DSPSVWAAVP GKTFVSITPA EVGVLVGKDR SSFFVNGLTL GGQKCSVIRD SLLQDGEFTM DLRTKSTGGA PTFNVTVTMT AKTLVLLMGK EGVHGGLINK KCYEMASHLR RSQY