Recombinant RING1B monoklonaal antilichaam

RING1B is a E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene regulation. H2AK119Ub gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. It may be involved in the initiation of both imprinted and random X inactivation. It E3 ubiquitin-protein ligase activity is enhanced by BMI1/PCGF4.

RING1B

Q9CQJ4

Human; Rat; Mouse

Recombinant human RING1B fragment

RNF; DinG; Ring1b; Rnf2

A531

Unconjugated

WB; IHC; IF; FCM

Protein A purified

1 mg/mL

WB 1:500-1:1000; IHC 1:200-1:1000; IF 1:50; FCM 1:50-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/xQIv4MKV

38 kDa

38 kDa

IgG, κ