Recombinant TDP43 Monoklonale Antilichaam

TAR DNA binding protein (TARDBP) Homo sapiens HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

TDP43

Q13148

Human; Mouse; Rat

Recombinant Human TDP43 protein

ALS; TDP; ALS10; TDP-43; TARDBP; TDP43; along with a truncated 20-28 kDa form; and 99% aa identity with rat TDP-43.; human and mouse TDP-43 share 100% aa sequence identity; in ubiquitin-containing inclusion bodies. TDP-43 can also influence CFTR exon 9 skipping in cystic fibrosis. Within aa 1-103; TDP-43 (TAR DNA binding protein of 43 kDa; TADBP

6F5

Unconjugated

WB

Microbiology; Neuroscience; Epigenetics and Nuclear Signaling

Protein A

0.2 mg/mL

WB 1:1000-1:5000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/RYEkpZfn

45 kDa

45 kDa

IgG, κ