Recombinant Ten-Eleven Translocase
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
DNA Methyltransferase
Chromatin/Epigenetic
Recombinant Ten-Eleven Translocase is a recombinantly expressed dioxygenase that depends on Fe (II) and α-ketoglutarate. It catalyzes the conversion of 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC), followed by further oxidation to 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) . Subsequently, 5caC is converted into uracil (U) through chemical or enzymatic processes, and during PCR, uracil (U) is transformed into thymine (T), allowing for single-base resolution and highly accurate identification of DNA methylation sites.
Ice Packs
-20°C
Beschrijving
Recombinant Ten-Eleven Translocase Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
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