Recombinant Ten-Eleven Translocase

Recombinant Ten-Eleven Translocase is a recombinant Fe (II) - and α-ketoglutarate-dependent dioxygenase. Recombinant Ten-Eleven Translocase converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), and then to 5-formylcytosine (5fC) and 5-carboxycytosine (5caC) through a series of oxidation reactions. Then, 5caC is further converted into uracil (U) through the action of a conversion agent or enzyme, and uracil (U) is converted into thymine (T) through PCR, thereby achieving single-base resolution and high-accuracy identification of DNA methylation sites[1].

12352204

TET Protein

Epigenetics

Others

[RecombinantTen-ElevenTranslocase]

[1]Liang J, et al. Ten-Eleven Translocation Family Proteins: Structure, Biological Functions, Diseases, and Targeted Therapy. MedComm (2020) . 2025 Jul 1;6 (7) :e70245.

Room temperature

Store at -20°C for 2 years

http://file.medchemexpress.com/batch_PDF/HY-E70583/Recombinant-Ten-Eleven-Translocase-SDS-MedChemExpress.pdf

Enzyme

No Development Reported