Recombinant TOP3B Monoklonale antilichamen

DNA topoisomerase 3-beta-1 (TOP3B), an enzyme that controls and alters the topologic states of DNA during transcription. TOP3B catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. TOP3B interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Low expression of TOP3B may be related to higher survival rates in breast cancer patients.

TOP3B

O95985

Human

Peptide. This information is proprietary to PTMab

TOP3B; TOP3B1

A690

Unconjugated

WB; IF

Epigenetics and Nuclear Signaling

Protein A purified

1 mg/mL

WB 1:1000-1:2000; IF 1:100-1:200

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/brMe0VWG

97 kDa

97 kDa

IgG, κ