Recombinant Ubiquitin K48 Monoklonale Antilichaam

This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.

Ubiquitin K48

P0CG47; P0CG48; P62979; P62987

Human; Mouse; Rat

Recombinant Human Ubiquitin K48 protein

HEL-S; UBB; HEL-S-50; ubiquitin B; Polyubiquitin-B; Ubiquitin; HEL-S-50; ubiquitin B

3F9

Unconjugated

WB

Cell Biology; Neuroscience; Epigenetics and Nuclear Signaling

Protein A

0.2 mg/mL

WB 1:500-1:2000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/jvjxZ0nN

26 kDa

13-250 kDa

IgG, κ