Recombinant vitamine D Multiklonaal antilichaamontvanger

This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins.

Vitamin D Receptor

P11473

Human; Mouse

Peptide. This information is proprietary to PTMab.

NR1I; nuclear receptor subfamily; PPP1R; member; VDR; NR1I1; PPP1R163; group I; member 1; nuclear receptor subfamily 1; vitamin D receptor

A789

Unconjugated

WB; IP

Epigenetics and Nuclear Signaling; Signal Transduction; Cancer

Protein A purified

1 mg/mL

WB 1:1000-1:3000; IP 1:50-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/7nVyDc4s

48 kDa

48 kDa

IgG, κ