Recombinante Caspase-14/CASP14 Monoklonale Antilichaam

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 7 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

CASP14

P31944

Human

Recombinant Human Caspase-14 / CASP14 protein

ARCI; Caspase; CASP14; ARCI12; CASP-14; Caspase-14; MGC119078; MGC119079

8D5

Unconjugated

IHC-P; ICC/IF

Cell Biology

Protein A

1 mg/mL

IHC-P 1:100-1:500; ICC/IF 1:20-1:100

0.2 μm filtered solution in PBS

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/jSxuM9dh

IgG