Recombinante Fosfo-Vimentin (Ser39) Monoklonale Antilichaam

Vimentin, also named as VIM, belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha (TNFA) and inhibited by the antiinflammatory cytokine IL10, suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein, 55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level.

Phospho-Vimentin (Ser39)

P08670

Human; Rat; Mouse

Phosphorylated human Vimentin (Ser39) peptide

HEL; Epididymis luminal protein; CTRCT; CTRCT30; HEL113; Vimentin; VIM; Epididymis luminal protein 113; VIME; FLJ36605; epididymis secretory sperm binding protein; CTRCT30; HEL113; vimentin; CTRCT30; Epididymis luminal protein 113; FLJ36605; HEL113; VIM; VIME; Vimentin

A820

Unconjugated

WB

Neuroscience; Signal Transduction; Stem Cells; Cancer; Developmental Biology

Protein A purified

1 mg/mL

WB 1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/9b0mUEMB

54 kDa

56 kDa

IgG, κ