Recombinante fosfor-AMPKα (Thr172) Monoklonale antilichamen

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK) . AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

PRKAA1

Q13131

Human

A synthetic peptide corresponding to the residues around

AMPK1; PRKAA1; Tau-protein kinase PRKAA1; HMGCR kinase; ACACA kinase; AMPK subunit alpha-1

11A7

Unconjugated

WB

Neuroscience; Signal Transduction; Cardiovascular; Cancer; Metabolism

Protein A

1 mg/mL

WB 1:2000-1:20000

10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/HN8Fnex9

62 kDa

67 kDa

IgG