Recombinante fosfor-IGF1R (Tyr1135/1136) /Fospho-Insulin Receptor β (Tyr1150/1151) Monoklonale Antilichaam

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

IGF1R

P06213; P08069

Human; Mouse; Rat

A synthetic peptide corresponding to residues around (Tyr1135/1136) / (Tyr1150/1151) of Human Phospho-IGF1R/Phospho-Insulin Receptor β

HHF; CD220; HHF5; INSR; IR; Insulin R; INSR; IR; Insulin Receptor; IGF IR; Insulin Receptor β

5C10

Unconjugated

WB

Signal Transduction; Neuroscience; Cancer; Cardiovascular; Metabolism; Developmental Biology

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/4xFYdJ6S

156 kDa

95 kDa

IgG, κ