Recombinante fosfor-JNK1, 2, 3 (Thr183, Thr183, Thr221) Monoklonale antilichamen

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation.

JNK1, 2, 3

P45983; P45984; P53779

Human; Mouse; Rat

A synthetic peptide corresponding to residues around (Thr183, Thr183, Thr221) of Human Phospho-JNK1, 2, 3

MAPK; PRKM; SAPK; JNK1A; JNK21B; MAPK8; JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c; AI849689; c Jun N terminal kinase 1; C-JUN kinase 1; c-Jun N-terminal kinase 1; EC 2.7.11.24; JNK 1; MAP kinase 8; MAPK 8; Mitogen activated protein kinase 8; mitogen-activated; Mitogen-activated protein kinase 8; MK08; p54 gamma; Protein kinase; Protein kinase JNK1; SAPK 1; SAPK gamma; Stress-activated protein kinase 1; Stress-activated protein kinase JNK1; JNK1/2/3

6H10

Unconjugated

WB

Signal Transduction; Cancer; Immunology; Epigenetics and Nuclear Signaling

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/x1UJ9KnZ

48 kDa

46,54 kDa

IgG, κ