Recombinante Human Allograft Inflammatory Factor 1/AIF1 (C-6His)

Source : E. coli; Allograft Inflammatory Factor 1 (AIF1) contains two EF-hand domains and exists as a homodimer. AIF1 can be detected in T-lymphocytes and peripheral blood mononuclear cells. AIF1 functions as actin-binding protein that enhances membrane ruffling and RAC activation and can enhance the actin-bundling activity of LCP1. In addition, AIF1 plays a role in RAC signaling and in phagocytosis and may also in macrophage activation and function. AIF1 promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes and plays a role in vascular inflammation.

Allograft Inflammatory Factor 1, AIF-1, Ionized Calcium-Binding Adapter Molecule 1, Protein G1, AIF1, G1, IBA1

Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl, pH7.4.

Ambient

Recombinant Human Allograft Inflammatory Factor 1 is produced by our E.coli expression system and the target gene encoding Ser2-Pro147 is expressed with a 6His tag at the C-terminus.