Recombinante muis Carnosine Dipeptidase 1/CNDP1-eiwit

Cndp1, as known as beta-Ala-His dipeptidase, is a member of the M20 metalloprotease family. In human, this protein is secreted from the liver into the serum. In other mammals, including rodents, it is expressed exclusively within the kidney and lacks a signal peptide. Also, it is a secreted homodimeric dipeptidase that specifically hydrolyzes L-carnosine, and is identified as human carnosinase expressed in the brain. Recombinant mouse Cndp1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Beta-Ala-His dipeptidase, CNDP dipeptidase 1, Carnosine dipeptidase 1, CN1, Carnosinase 1

Baculovirus

Mouse

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

56.1 kDa (500aa)

AI746433, Beta Ala His dipeptidase, Beta-Ala-His dipeptidase, Carnosinase 1, Carnosinase1, Carnosine dipeptidase 1, Carnosine dipeptidase1, CN 1, CN1, CN-1, CNDP 1, CNDP dipeptidase 1, CNDP dipeptidase1, CNDP1, CNDP-1, ATGP3408-10 µg, ATGP3408-20 µg, ATGP3408-50 µg, ATGP3408-100 µg, ATGP3408-250 µg, ATGP3408-500 µg, ATGP3408-1 mg, ATGP3408-010, ATGP3408-020, ATGP3408-050, ATGP3408-100, ATGP3408-250, ATGP3408-500, ATGP3408-01M

Janssen B., et al, (2005) Diabetes. 54:2320-2327.; ; Teufel M., et al, (2003) J. Biol. Chem. 278:6521-6531.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Signal Transduction

NP_803233

Q8BUG2

Mouse

Met1