Recombinante muis CCL2/MCP-1-eiwit

Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1) . CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Recombinant mouse CCL2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Chemokine (C-C motif) ligand 2, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, MCP-1, Platelet-derived growth factor-inducible protein JE, Small-inducible cytokine A2, Je, Mcp1, Scya2, HC11, MCAF, Sigje, SMC-CF

E.coli

Mouse

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

16 kDa (146aa) confirmed by MALDI-TOF

CCL2, JE, MCP1, ATGP2074-10 µg, ATGP2074-20 µg, ATGP2074-50 µg, ATGP2074-100 µg, ATGP2074-250 µg, ATGP2074-500 µg, ATGP2074-1 mg, ATGP2074-10, ATGP2074-20, ATGP2074-50, ATGP2074-100, ATGP2074-250, ATGP2074-500, ATGP2074-1

Foresti ML, Arisi GM, et al. (2009) . J Neuroinflammation. 6:40.; ; Semple BD, Bye N, et al. (2010) . J Cereb Blood Flow Metab. 30 (4) :769-82.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) 10% glycerol

Hormones & Cytokines

NP_035463

P10148

Mouse

QPDAVNAPL TCCYSFTSKM IPMSRLESYK RITSSRCPKE AVVFVTKLKR EVCADPKKEW VQTYIKNLDR NQMRSEPTTL FKTASALRSS APLNVKLTRK SEANASTTFS TTTSSTSVGV TSVTVN