Recombinante muis CREG/CREG1-eiwit

Creg1, also known as Cellular repressor of E1A-stimulated genes1, was antagonizes transcriptional activation and cellular transformation by E1A. This protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. Creg1 increases EC filopodia formation and vascular assembly via ILK-Cdc42 activation and promotes neovascularization, which might be a therapeutic target for ischemic injury. Recombinant mouse Creg1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Cellular repressor of E1A-stimulated genes1, AA755314, Creg

E.coli

Mouse

His-Tag

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

> 95% by SDS-PAGE

24 kDa (213aa)

Creg1, Cellular repressor of E1A-stimulated genes1, AA755314, Creg, ATGP3512-10 µg, ATGP3512-20 µg, ATGP3512-50 µg, ATGP3512-100 µg, ATGP3512-250 µg, ATGP3512-500 µg, ATGP3512-1 mg, ATGP3512-10, ATGP3512-20, ATGP3512-50, ATGP3512-100, ATGP3512-250, ATGP3512-500, ATGP3512-1

Wang, N., et al. (2011) Atherosclerosis. 218 (2) :543-51 ; ; Yan C., et al. (2014) Front Biosci. 19:1151-61.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol

Cancer

NP_035934

O88668

Mouse

MGSSHHHHHH SSGLVPRGSH MGSMRGGRDH GDWDVDRRLP PLPPREDGPR VARFVTHVSD WGSLATISTI KEVRGWPFAD IISISDGPPG EGTGEPYMYL SPLQQAVSDL QENPEATLTM SLAQTVYCRN HGFDPQSPLC VHIMMSGTVT KVNKTEEDYA RDSLFVRHPE MKHWPSSHNW FFAKLKISRI WVLDYFGGPK VVTPEEYFNV TLQ