Recombinante muis Pentraxine 2/PTX2-eiwit

Pentraxin2, also known as serum amyloid P-component, is a secreted serum glycoprotein that belongs to the pentraxins family. This family binds calcium-dependent lectin-like manner and is characterized distinctive flattened Beta-jellyroll structure similar to the legume lectins. This protein is a non-fibrillar component, it can interact with DNA and histones. It regulates the solubility of amyloid fibrils and protects them from degradation by proteolytic enzymes and phagocytic cells. This protein is the major acute-phase protein and expression of it is dependent on complement activation, IL-6 and/or IL-1 beta. Recombinant mouse Pentraxin2 protein, fused to His-tag at C-terminus, was expressed in HEK293 and purified by using conventional chromatography techniques.

Serum amyloid P-component, SAP, Apcs, Sap

HEK293

Mouse

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

24.6 kDa (210aa)

Pentraxin2, SAP, Pentraxin2/SAPSerum amyloid P-component, SAP, Apcs, Sap, ATGP3858-10 µg, ATGP3858-20 µg, ATGP3858-50 µg, ATGP3858-100 µg, ATGP3858-250 µg, ATGP3858-500 µg, ATGP3858-1 mg, ATGP3858-10, ATGP3858-20, ATGP3858-50, ATGP3858-100, ATGP3858-250, ATGP3858-500, ATGP3858-1

Xi D., et al, (2015) Int J Cardiol. 187:20-26.; ; Muczynski V., et al, (2017) Blood. 101 (9) : 129 (17) :2443-2454.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Neuroscience

NP_035448

P12246

Mouse

Gln21