Recombinatie ACE2 monoklonaal antilichaam

ACE2 is a carboxypeptidase that catalyses the conversion of angiotensin I to angiotensin 1-9, or of angiotensin II to the vasodilator angiotensin 1-7. ACE2 is a critical component in the renin-angiotensin system (RAS) . ACE2 is predominantly expressed in vascular endothelial cells of the heart and kidney and Leydig and Sertoli cells of the testis. The unique expression pattern of ACE2 determines its essential role in the regulation of cardiovascular and kidney functions, as well as fertility. ACE2 protein is localized mainly in the extracellular space with its carboxy-terminal end attached to the membrane via its transmembrane domain. Active ACE2 enzyme is secreted by cleavage at the amino terminus. Research studies have shown that ACE2 expression is elevated in human failing heart. ACE2 has also been identified as the receptor for SARS and SARS-CoV-2 coronaviruses.

ACE2

Q9BYF1

Human; Mouse

Peptide. This information is proprietary to PTMab.

ACE; UNQ; PRO; Metalloprotease MPROT; Angiotensin-converting enzyme; ACE2; ACEH; ACEII; Angiotensin-converting enzyme 2; Angiotensin-converting enzyme homolog; Angiotensin-converting enzyme-related carboxypeptidase; ACE-related carboxypeptidase; Metalloprotease MPROT15; Processed angioten; UNQ868; PRO1885; ACEH; angiotensin-converting enzyme 2; ACE 2; ACE related carboxypeptidase; Angiotensin converting enzyme 2; Angiotensin converting enzyme homolog; Angiotensin converting enzyme like protein; Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2; Angiotensin I converting enzyme 2; DKFZP434A014; EC 3.4.17; metalloprotease MPROT 15; OTTHUMP00000022963; Processed angiotensin-converting enzyme 2

A708

Unconjugated

WB; IHC

Cell Biology; Cardiovascular

Protein A purified

1 mg/mL

WB 1:1000; IHC 1:500-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/QVBDSyyS

92 kDa

100, 120 kDa

IgG, κ