Recombinatie Aconitase 1 / ACO1 monoklonaal antilichaam

Aconitase 1 is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA.

Aconitase 1/ACO1

P21399

Human; Rat; Mouse

Recombinant human Aconitase 1/ACO1 fragment

HEL; IRP; ACO; IREB; ACO1; ACONS; HEL60; IREB1; IREBP; IREBP1; IRP1; ACO 1; ACOC; Aconitase; Aconitase 1 soluble; Aconitase1; Aconitate hydratase; Citrate hydro lyase; Citrate hydro-lyase; Cytoplasmic aconitate hydratase; Ferritin repressor protein; IRE BP 1; IREB 1; IRE-BP 1; Iron regulatory protein 1; Iron responsive element binding protein 1; Iron-responsive element-binding protein 1; IRP 1; OTTHUMP00000045233

A583

Unconjugated

WB

Cardiovascular; Signal Transduction; Epigenetics and Nuclear Signaling; Metabolism

Protein A purified

1 mg/mL

WB 1:500-1:2000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/W0zYW8CB

98 kDa

105 kDa

IgG, κ