Recombinatie ADSL / Adenylosuccinaat Lyase monoklonaal antilichaam

Adenylosuccinate lyase, also known as adenylosuccinase, ADSL or ASL, is an enzyme implicated in the reaction of adenylosuccinat converting to AMP and fumarate as part of the purine nucleotide cycle. The two substates of adenylosuccinate lyase (ADSL) are dephosphorylated derivatives of SAICA ribotide (SAICAR) and adenylosuccinate (S-AMP), which catalyzes an important reaction in the de novo pathway of purine biosynthesis. ADSL catalyzes two distinct reactions in the synthesis of purine nucleotides, both of which involve the _-elimination of fumarate to produce either aminoimidazole carboxamide ribotide from SAICAR or AMP from S-AMP. The Adenylosuccinate lyase deficiency is a rare autosomal recessive metabolic disorder characterized by the present of SAICA riboside and succinyladenosine (S-Ado) . ADSL defect in different patients is often caused by different mutations to the enzyme.

ADSL

P30566

Human

Recombinant Human ADSL/Adenylosuccinate Lyase protein

ASASE; ASL; AMPS; ADSL

9D3

Unconjugated

WB; ICC/IF; IP

Signal Transduction; Metabolism

Protein A

1 mg/mL

WB 1:500-1:2000; ICC/IF 1:20-1:100; IP 1-4 μL/mg of lysate

0.2 μm filtered solution in PBS

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/PLsKmdo9

55 kDa

55 kDa

IgG