Recombinatie alfa-Galactosidase A / GLA monoklonaal antilichaam

Alpha -Galactosidase A is a homodimeric glycoprotein that can release terminal alpha -galactosyl moieties from glycolipids and glycoproteins and catalyze the hydrolysis of melibiose into galactose and glucose . It is a lysosomal enzyme and is responsible for degradation of glycolipid globotriaosylceramide (Gb3) (Gal alpha 1‑4Gal beta 1‑4Glc beta ‑ceramide) . Mutations in this gene cause Fabry disease, an X-linked hereditary lysosomal storage disease with the accumulation of Gb3 in the walls of small blood vessels, nerves, dorsal root ganglia, renal glomerular and tubular epithelial cells, and cardiomyocytes .

GLA

P06280

Human

Recombinant Human alpha-Galactosidase A/GLA protein

GLA; GALA; Alpha-D-Galactoside; Galactohydrolase; galactosidase alpha; GLAL; Melibiase; Agalsidase; Alpha-galactosidase A; Alpha-D-galactosidase A; Alpha-D-galactoside galactohydrolase; Galactosylgalactosylglucosylceramidase GLA

5D11

Unconjugated

WB

Cardiovascular

Protein A

1 mg/mL

WB 1:500-1:2000

0.2 μm filtered solution in PBS

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/PlN40HqX

49 kDa

49 kDa

IgG