Recombinatie ALIX monoklonaal antilichaam

Programmed cell death 6-interacting protein (PDCD6IP), plays an important role in the endosomal sorting complexes required for transport (ESCRT) pathway in the abscission stage of cytokinesis and apoptosis. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the protein binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. It also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this protein and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death.

ALIX

Q8WUM4

Human; Rat; Mouse

Recombinant human ALIX fragment

AIP; DRIP; KIAA; PDCD6IP; AIP1; ALIX; DRIP4; HP95; KIAA1375

A493

Unconjugated

WB; IHC; IP

Cell Biology; Microbiology; Signal Transduction

Protein A purified

1 mg/mL

WB 1:2000-1:10000; IHC 1:100-1:500; IP 1:25-1:50

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/x1OHGAY4

96 kDa

90/100 kDa

IgG, κ