Recombinatie ARpc5 / p16 ARC monoklonaal antilichaam

Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) . The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) .

ARPC5/p16 ARC

O15511

Human; Rat; Mouse

Recombinant human ARPC5/p16 ARC fragment

ARC; ARPC; dJ127C; ARPC5; ARC16; dJ127C7.3; p16-Arc

A319

Unconjugated

WB; IHC; IF; FCM

Signal Transduction

Protein A purified

1 mg/mL

WB 1:500-1:2000; IHC 1:50-1:100; IF 1:50; FCM 1:50

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/QVcqf9VC

16 kDa

16 kDa

IgG, κ