Recombinatie ATF1 monoklonaal antilichaam

ATF-1 is a bZIP transcription factor that is a member of the cyclic AMP (cAMP) -response element-binding protein (CREB) family. Like other members of the CREB family, ATF-1 mediates signals from numerous physiological stimuli and activates target genes through cAMP-response elements, resulting in the regulation of a broad array of cellular responses. ATF-1 can be phosphorylated at Ser63 by protein kinase A (PKA), calmodulin-dependent protein kinase (CaMK), and cyclin-dependent kinase 3 (CDK3), which recruits CBP/p300 and enhances transcriptional activity. ATF-1 expression levels have been found to be elevated in lymphomas and metastatic melanoma cells, where it contributes to tumor growth.

ATF1

P81269

Human; Rat; Mouse

Recombinant human ATF1 fragment

ATF; Atf1

A562

Unconjugated

WB; IHC; IF; FCM

Protein A purified

1 mg/mL

WB 1:500-1:1000; IHC 1:100-1:1000; IF 1:50; FCM 1:50-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/CS9QqMdH

29 kDa

35 kDa

IgG, κ