Recombinatie ATG4B monoklonaal antilichaam

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

ATG4B

Q9Y4P1

Human; Mouse

Recombinant human ATG4B fragment

AUTL; KIAA; ATG4B; APG4B; AUTL1; cysteine protease ATG4B; KIAA0943; APG4B; AUTL1; cysteine protease ATG4B; APG4 autophagy 4 homolog B; ATG4 autophagy related 4 homolog B (S. cerevisiae) ; AUT like 1 cysteine endopeptidase; AUT-like 1 cysteine endopeptidase; Autophagin 1; Autophagin-1; Autophagy related 4B cysteine peptidase; Autophagy related cysteine endopeptidase 1; Autophagy related protein 4 homolog B; Autophagy-related cysteine endopeptidase 1; Autophagy-related protein 4 homolog B; hAPG4B; MGC1353

A343

Unconjugated

WB; IF

Cancer; Cell Biology; Cardiovascular; Metabolism

Protein A purified

1 mg/mL

WB 1:500-1:1000; IF 1:50

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/ScMAMz98

48 kDa

48 kDa

IgG, κ