Recombinatie ATM monoklonaal antilichaam

The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.

Atm

Q13315

Human; Mouse; Rat

Recombinant Human ATM protein

TEL; TELO; AT1; ATA; ATC; ATD; ATDC; ATE; TEL1; TELO1; ATM; AT mutated; A-T mutated; A-T mutated homolog; Ataxia telangiectasia mutated; Ataxia telangiectasia mutated gene; Ataxia telangiectasia mutated homolog; Ataxia telangiectasia mutated homolog (human) ; ATM serine/threonine kinase; DKFZp781A0353; homolog; MGC74674; OTTHUMP00000232981; Serine protein kinase ATM; Serine/threonine-protein kinase ATM; Serine-protein kinase ATM; Tefu; Telomere fusion protein; telomere maintenance 1

3P12

Unconjugated

WB

Epigenetics and Nuclear Signaling; Cancer

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/dia0fwPQ

351 kDa

351 kDa

IgG, κ