Recombinatie B7-H3 / CD276 monoklonaal antilichaam

May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.

B7-H3/CD276

Q5ZPR3

Human; Mouse

Recombinant human B7-H3/CD276 fragment

B7H; UNQ; PRO; B7-H; B7RP; B7 homolog; B7H34Ig-B7-H; PSEC;4Ig-B7-H; CD276;4Ig-B7-H3; B7-H3; B7H3; B7RP-2; B7 homolog 3; B7H34Ig-B7-H3; CD276 antigen; CD276 molecule; Costimulatory molecule; PSEC0249; UNQ309; PRO352; B7RP-2;4Ig-B7-H3; B7H3; B7-H3; CD276 antigen

A137

Unconjugated

WB; IHC; IF; FCM; IP

Immunology; Cancer; Stem Cells

Protein A purified

1 mg/mL

WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:50; FCM 1:50-1:100; IP 1:25-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/WcwwuI6Q

57 kDa

110 kDa

IgG, κ